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Cat. Number
Cyanine5 DBCO
Chemical Name
Cyanine5 DBCO
Mol. Formula
C53H59N4F6O2P
Mol. Weight
929.03
Qty 1
5mg
Qty 2
10mg
Appearance
dark blue solid
Solubility
good in DMF, DMSO, chlorinated organic solvents
Storage condition
-20°C
References

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

Spectral properties

Excitation maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2