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Cat. Number

Cy5 胺 Cyanine5 amine

Chemical Name

Cy5 胺 Cyanine5 amine

Mol. Formula

C38H54Cl2N4O

Mol. Weight

653.77

Qty 1

5mg

Qty 2

25mg

Appearance

dark blue powder

Solubility

moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Storage condition

-20°C

References

Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.

This bright and photostable dye is suitable for many different methods of fluorescence detection. Colorful fluorophore can also be easily detected in small quantities (nanomols) by naked human eye.

Spectral properties

Excitation maximum, nm:	646
ε, L⋅mol−1⋅cm−1:	250000
Emission maximum, nm:	662
Fluorescence quantum yield:	0.2

Product citations

Chen, G.; Wang, Y.; Xie, R.; Gong, S. Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery. Journal of Controlled Release, in press. doi: 10.1016/j.jconrel.2017.01.042
Wang, Y.; Wang, L.; Chen, G.; Gong, S. Carboplatin-Complexed and cRGD-Conjugated Unimolecular Nanoparticles for Targeted Ovarian Cancer Therapy. Macromolecular Bioscience, in press. doi:10.1002/mabi.201600292
Zhang, R.; Yang, J.; Radford, D.C.; Fang, Y.; Kopeček, J. FRET Imaging of Enzyme-Responsive HPMA Copolymer Conjugate. Macromolecular Bioscience, 2017, 17(1), 1600125. doi: 10.1002/mabi.201600125
Pombo-García, K.; Weiss, S.; Zarschler, K.; Ang, C.-S.; Hübner, R.; Pufe, J.; Meister, S.; Seidel, J.; Pietzsch, J.; Spiccia, L.; Stephan, H.; Graham, B. Zwitterionic polymer-coated ultrasmall superparamagnetic iron oxide nanoparticles with low protein interaction and high biocompatibility. ChemNanoMat, 2016, 2(10), 959–971. doi: 10.1002/cnma.201600233

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