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Cat. Number
Cyanine3 amine
Chemical Name
Cyanine3 amine
Mol. Formula
C36H52Cl2N4O
Mol. Weight
627.73
Qty 1
5mg
Qty 2
25mg
Appearance
red powder
Solubility
moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Storage condition
-20°C
References

Cyanine3 amine is a functionalized cyanine dye containing a free amino group. Cyanine3 is an analog of Cy3®.

Amino group of this reagent can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

The amino dye is supplied in salt form, and possesses some aqueous solubility.

Spectral properties

Excitation maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31

Product citations

  1. Wilson, D.R.; Mosenia, A.; Suprenant, M.P.; Upadhya, R.; Routkevitch, D.; Meyer, R.A.; Quinones-Hinojosa, A.; Green, J.J. Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino ester)/DNA Nanoparticles for Enhanced Gene Delivery. Journal of Biomedical Materials Research. Part A, in press. doi:10.1002/jbm.a.36033

  2. Guldris, N.; Argibay, B.; Gallo, J.; Iglesias-Rey, R.; Carbó-Argibay, E.; Kolen'ko, Y.V.; Campos, F.; Sobrino, T.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Magnetite Nanoparticles for Stem Cell Labeling with High Efficiency and Long-Term in Vivo Tracking. Bioconjugate Chemistry2017, 28(2), 362–370. doi:10.1021/acs.bioconjchem.6b00522

  3. Guldris, N.; Argibay, B.; Kolen'ko, Y.V.; Carbó-Argibay, E.; Sobrino, T.; Campos, F.; Salonen, L.M.; Bañobre-López, M.; Castillo, J.; Rivas, J. Influence of the Separation Procedure on the Properties of Magnetic Nanoparticles: Gaining in vitro Stability and T1‐T2 Magnetic Resonance Imaging Performance.Journal of Colloid and Interface Science2016, 472, 229–236. doi: 10.1016/j.jcis.2016.03.040

  4. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry2016, 7(17), 3046–3055;. doi:10.1039/c6py00518g

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