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Cat. Number
Cyanine3 alkyne
Chemical Name
Cyanine3 alkyne
Mol. Formula
C33H40ClN3O
Mol. Weight
530.14
Qty 1
5mg
Qty 2
10mg
Appearance
red powder
Storage condition
-20°C
References

Cyanine3 alkyne is a fluorophore ready for the use in Click Chemistry reaction.

With this reagent, bright and photostable Cyanine3 reporter, an analog of Cy3®, can be attached to nearly any molecule bearing azide group.

This alkyne is non water-soluble. However, when used with organic co-solvent (DMSO or DMF), this dye can be efficiently attached to water-soluble molecules such as proteins, or peptides.

Product citations

  1. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, in press. doi:10.1074/jbc.M116.726752

  2. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051

  3. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g

  4. Vanparijs, N.; De Coen, R.; Laplace, D.R.; Louage, B.; Maji, S.; Lybaert, L.; Hoogenboom, R.; De Geest, B. Transiently responsive protein-polymer conjugates via a grafting-from RAFT approach: for intracellular co-delivery of proteins and immune-modulators.Chemical Communications2015, 51, 13972–13975. doi: 10.1039/c5cc04809e

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