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Cat. Number
TAMRA azide, 5-isomer
Chemical Name
TAMRA azide, 5-isomer
CAS Number
825651-66-9
Mol. Formula
C28H28N6O4
Mol. Weight
512.56
Qty 1
5mg
Qty 2
10mg
Appearance
violet solid / solution
Storage condition
-20°C
References

TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.

TAMRA is often used as FRET acceptor for FAM fluorophore.

Can replace Alexa Fluor 555, DyLight 549.

Product citations

  1. Zhou, Y.; Li, W.; Wang, M.; Zhang, X.; Zhang, H.; Tong, X.; Xiao, Y. Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics. Molecular BioSystems2017, 13(1), 83–91. doi: 10.1039/c6mb00691d

  2. Zuhl, A.M.; Nolan, C.E.; Brodney, M.A.; Niessen, S.; Atchison, K.; Houle, C.; Karanian, D.A.; Ambroise, Cl.; Brulet, J.W.; Beck, E.M.; Doran, S.D.; O'Neill, B.T.; am Ende, C.W.; Chang, C.; Geoghegan, K.F.; West, G.M.; Judkins, J.C.; Hou, X.; Riddell, D.R.; Johnson, D.S. Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors. Nature communications2016, 7, 13042. doi: 10.1038/ncomms13042

  3. Rana, S.; Blowers, E.C.; Tebbe, C.; Contreras, J.I.; Radhakrishnan, P.; Kizhake, S.; Zhou, T.; Rajule, R.N.; Arnst, J.L.; Munkarah, A.R.; Rattan, R.; Natarajan, A. Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study. Journal of Medicinal Chemistry2016, 59(10), 5121–5127. doi:10.1021/acs.jmedchem.6b00400

  4. Zhou, Y.; Li, W.; Xiao, Y. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. ACS Chemical Biology2016, 11(4), 882–888. doi: 10.1021/acschembio.5b01043

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