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| Cat. Number | A0919 |
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| Chemical Name | L-乙酰基肉碱 Acetyl-L-carnitine |
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| CAS Number | 3040-38-8 |
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| Mol. Formula | C9H17NO4 |
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| Mol. Weight | 203.24 |
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| Qty 1 |
1g |
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| Qty 2 | 5g |
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| Application Notes | ≥98% |
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| References |
Description
Acetyl-L-carnitine is a natural derivative of carnitine that enables functions of CoA and plays a significant role in the maintenance of energy homeostasis. Acetyl-L-carnitine exhibits antidepressant, neuroprotective, analgesic, and antinociceptive activities. In vivo, acetyl-L-carnitine acetylates p65, inducing NF-κB-mediated upregulation of mGluR2 receptors. In neuron-like PC12 cells, acetyl-L-carnitine inhibits 3-NPA-produced cellular stress responses and neurotoxicity. Acetyl-L-carnitine normalizes brain levels of neurotrophic factors such as NGF, GDNF, and artemin in animal models of neuropathy. Additionally, acetyl-L-carnitine exhibits some degree of antinociceptive benefit through indirect modulation of M1 muscarinic acetylcholine receptors (mAChRs). In cellular models of Alzheimer
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