当前您的位置:首页>>生物化学试剂>>信号转导>>TGF-β RI Kinase Inhibitor II (RepSox)
Cat. Number
TGF-β RI Kinase Inhibitor II (RepSox)
Chemical Name
TGF-β RI Kinase Inhibitor II (RepSox)
Mol. Formula
C17H13N5
Mol. Weight
287.3
Qty 1
2mg
Appearance
Yellowish solid.
Application Notes
≥98%
Solubility
5mg/ml soluble in DMSO or methanol
Storage condition
-20°C
Stability
Stable for 2 years after receipt when stored at -20°C
References

Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50>16µM). Replace Sox2 during reprogramming mouse embryonic fibroblasts transduced with Oct4, Klf4 and c-Myc1,2.

Product Specification:

Formula: C17H13N5

MW: 287.3 

Purity: ≥98% 

Appearance: Yellowish solid. 

Solubility: 5mg/ml soluble in DMSO or methanol. 

Shipping: AMBIENT 

Long Term Storage: -20°C 

Use/Stability: Stable for 2 years after receipt when stored at -20°C. Stock solutions are stable for up to 6 months when stored at -20°C.