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Cat. Number
H1619-001
Chemical Name
H1619-001 N-Dodecanoyl-NBD-sphingosylphosphorylcholine (mixture of D-erythro and L-threo isomers)
Category
semi-synthetic
Mol. Formula
C41H73N6O9P
Mol. Weight
825
Qty 1
1mg
Appearance
solid
Application Notes
98+% TLC
Synonym
N-C12:0-NBD-Sphingomyelin; N-C12:0-NBD-Sphingosylphosphorylcholine
Solubility
chloroform/methanol,2:1;methanol
Storage condition
-20°C
References

1. A. Loidl et al. “High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates” Journal of Lipid Research, vol. 43 pp. 815-823, 2002
2. C. St Clair et al. “The probability of neonatal respiratory distress syndrome as a function of gestational age and lecithin/sphingomyelin ratio” Am J Perinatol., Vol. 25(8) pp. 473-480, 2008,
3. J. Kilkus et al. “Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons” J Neurochem. Vol. 106(4) pp. 1745- 1757, 2008
4. N. Duan RD. “Absorption and lipoprotein transport of sphingomyelin” J Lipid Res., Vol. 47(1) pp. 154-171, 2006
5. R. Veldman et al. “N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx” Nature, vol. 90 pp. 917-925, 2004
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