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Cat. Number
H2200
Chemical Name
H2200 N-1-13C-Hexadecanoyl-sphingosylphosphorylcholine
Category
semisynthetic
Mol. Formula
12C3813CH79N2O6P
Mol. Weight
703
Qty 1
1mg
Appearance
solid
Application Notes
98+% TLC
Synonym
D-erythro-Spingomyelin with 1-13C-palmitic acid; N-1-13C-Palmitoyl-sphingosylphosphorylcholine
Solubility
chloroform, methanol, ethanol
Storage condition
-20°C
References

1. R. N. Kolesnick, A. Haimovitz-Friedman, Z. Fuks “The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation” Biochem Cell Biol., Vol. 72(11-12) pp. 471-474, 1994
2. M. Schmuth, et al. “Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis” J Invest Dermatol., Vol. 115(3) pp. 459-466, 2000
3. C. St Clair et al. “The probability of neonatal respiratory distress syndrome as a function of gestational age and lecithin/sphingomyelin ratio” Am J Perinatol., Vol. 25(8) pp. 473-480, 2008,
4. J. Kilkus et al. “Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons” J Neurochem. Vol. 106(4) pp. 1745- 1757, 2008
5. N. Duan RD. “Absorption and lipoprotein transport of sphingomyelin” J Lipid Res., Vol. 47(1) pp. 154-171, 2006
6. R. Veldman et al. “N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx” Nature, Vol. 90 pp. 917-925, 2004
下一个：N-Acetyl-sphingosylphosphorylcholine (mixture of D-erythro and L-threo isomers)上一个：Tetradecenoic acid (cis-9)
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