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Cat. Number
H1330-1
Chemical Name
H1330-1 植物鞘鞍醇 Phytosphingosine 554-62-1
CAS Number
554-62-1
Category
natural
Mol. Formula
C18H39NO3
Mol. Weight
318
Qty 1
1g
Appearance
solid
Application Notes
98+% TLC; GC
Synonym
4-Hydroxysphinganine
Solubility
ethanol, methanol, chloroform/methanol, 2:1(warm)
Storage condition
-20°C
References

1. K. Liu et al. “The Sphingoid Long Chain Base Phytosphingosine Activates AGC-type Protein Kinases in Saccharomyces cerevisiae Including Ypk1, Ypk2, and Sch9” Journal of Biological Chemistry, Vol. 280(24) pp. 22679, 2005
2. K. Ryu et al. “Anti-scratching Behavioral Effects of N-Stearoylphytosphingosine and 4-Hydroxysphinganine in Mice” Lipids, Vol. 45 pp. 615-618, 2010
3. M. Park et al. “Suppression of Extracellular Signal-related Kinase and Activation of p38 MAPK Are Two Critical Events Leading to Caspase-8- and Mitochondria-mediated Cell Death in Phytosphingosine-treated Human Cancer Cells” Journal of Biological Chemistry, Vol. 278, pp. 50624-50634, 2003
4. N. Chung et al. “Phytosphingosine as a Specific Inhibitor of Growth and Nutrient Import in Saccharomyces cerevisiae” Journal of Biological Chemistry, Vol. 276 pp. 35614-35621, 2001
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