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Cat. Number
H2043
Chemical Name
H2043 N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine
Category
synthetic
Mol. Formula
C30H61N04
Mol. Weight
500
Qty 1
5mg
Appearance
solid
Application Notes
98+% GC,TLC
Synonym
N-(R,S)-alpha-Hydroxy-C12:0-D-erythro-dihydroceramide
Solubility
chloroform/methanol/water, 2:1:0.5
Storage condition
-20°C
References

1. Y. Mizutani, A. Kihara, and Y. Igarashi “Identifcation of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation” FEBS Letters, vol. 563 pp. 93-97, 2004
2. Z. Szulc et al. “Synthesis, NMR characterization and divergent biological actions of 2-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells” Bioorg Med Chem, vol. 18 pp. 7565-7579, 2010
3. M. Kruer et al. “Defective FA2H leads to a novel form of neurodegeneration with brain iron accumulation (NBIA)” Annals of Neurology, vol. 68 pp. 611- 618, 2010
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