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Cat. Number
H1631-001
Chemical Name
H1631-001 N-Dodecanoyl-NBD-ceramide trihexoside
Category
semisynthetic
Mol. Formula
C54H91N5O21
Mol. Weight
1145
Qty 1
1mg
Appearance
solid
Application Notes
98+% TLC
Synonym
N-C12:0-NBD-CTH; N-C12:0-NBD-Globotriaosylceramide
Solubility
DMSO, hot methanol, chloroform/methanol, 2:1
Storage condition
-20°C
References

1. J. Kok et al. “Dihydroceramide Biology STRUCTURE-SPECIFIC METABOLISM AND INTRACELLULAR LOCALIZATION” Journal of Biological Chemistry, Vol. 272 pp. 21128-21136, 1997
2. J. Hsu et al. “Enhanced endothelial delivery and biochemical effects of -galactosidase by ICAM-1-targeted nanocarriers for Fabry disease” Journal of Controlled Release, doi:10.1016/j.jconrel.2010.10.031, 2010
3. J. E. Groener, B. J. Poorthuis, S. Kuiper, M. T. Helmond, C. E. Hollak, J. M. Aerts. “HPLC for simultaneous quantification of total ceramide, glucosylceramide, and ceramide trihexoside concentrations in plasma.” Clin Chem., Apr;53(4):742-7, 2007. Epub Mar 1 2007
4. K. Mills, A. Johnson, B. Winchester. “Synthesis of novel internal standards for the quantitative determination of plasma ceramide trihexoside in Fabry disease by tandem mass spectrometry.” FEBS Lett., Mar 27;515(1-3):171-6, 2002
5. C. Menge, I. Stamm, M. Wuhrer, R. Geyer, L. H. Wieler, G. Baljer. “Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro.” Vet Immunol Immunopathol., Nov;83(1-2):19-36, 2001
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