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Cat. Number
TKC0006
Chemical Name
Cabozantinib
CAS Number
849217-68-1
Mol. Weight
501.51
Synonym
XL-184, BMS-907351
Solubility
in DMSO (≥117mg/mL), insoluble in water (≤1 mg/mL)
References

Cabozantinib or XL-184 is a tyrosine kinase (c-MET, VEGFR2) inhibitor.  It has been shown to reduce tumor growth, metastasis, angiogenesis, and induce apoptosis.

Yakes FM, Chen J, Tan J, et al.  Mol Cancer Ther. 10:2298-308 (2011).
Agarwal N, Sonpavde G, Sternberg CN. Eur Utol 61:950-60 (2012).

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