Rosiglitazone-d5 Maleate_上海惠诚生物生物试剂,标准品,仪器设备,耗材,一站式服务

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Cat. Number

702016892702384

Chemical Name

Rosiglitazone-d5 Maleate

References

Molecular Formula	C₂₂H₁₈D₅N₃O₇S
Formula Weight	412.9
Purity	>99% deuterated product
Stability	1 year
Storage	4°C
Shipping	Wet icein continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard OC(=O)\C=C\C(=O)O.O=C1SC(Cc2ccc(OCCN(C)c3ccccn3)cc2)C(=O)N1

Size	Global Purchasing
1 mg
5 mg
10 mg

Description

Rosiglitazone is an anti-diabetic drug from the thiazolidinedione class. Like other thiazolidinediones, its mechanism of action is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ. Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. Apart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear factor κ-B (NF-κB) levels fall and inhibitor (IκB) levels increase in patients on rosiglitazone.

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