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Cat. Number

HMYB01500

Chemical Name

Nicotinamide 烟酰胺

CAS Number

98-92-0

Mol. Formula

C6H6N2O

Mol. Weight

122.12644

Qty 1

500mg

Application Notes

HPLC≥99.0%

Synonym

Niacinamide；Nicotinic acid amide；Pyridine-3-carboxylic acid amide；Vitamin PP；Vitamin B3

References

Nicotinamide 烟酰胺，是b族维生素家族的重要成员。它是烟酸的衍生物，有时被称为维生素B3。烟酰胺是一种水溶性维生素，这意味着它不会储存在体内，必须定期从饮食来源或补充剂中摄入。它参与许多细胞过程，包括能量代谢、DNA修复和基因表达。烟酰胺已被研究其潜在的治疗应用，包括治疗糖尿病、神经退行性疾病和癌症。

Nicotinamide烟酰胺可抑制 SIRT2 的体外活性，其 EC50 值为 2μM。烟酰胺可抑制 90% 的黑色素瘤细胞数量，并增加细胞内 NAD+、ATP、ROS 水平。烟酰胺抑制黑色素瘤小鼠的肿瘤生长并提高生存率，可用于黑色素瘤等皮肤癌相关的研究。

订购信息：

产品名称	纯度	规格
Nicotinamide烟酰胺	>99%	500mg
Nicotinamide烟酰胺	>99%	5g
Nicotinamide烟酰胺	>99%	50g

产品信息：

CAS RN	98-92-0
Product Name	Nicotinamide
Molecular Formula	C6H6N2O
Molecular Weight	122.12g/mol
IUPAC Name	pyridine-3-carboxamide
InChI	InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI Key	DFPAKSUCGFBDDF-UHFFFAOYSA-N
SMILES	C1=CC(=CN=C1)C(=O)N
Canonical SMILES	C1=CC(=CN=C1)C(=O)N
Appearance	Nicotinamide is a white powder. (NTP, 1992),DryPowder; OtherSolid,Solid,WHITE CRYSTALLINE POWDER.
Boiling Point	302 to 320 °F at 760 mm Hg (NTP, 1992) 157 °C at 5.00E-04 mm Hg
Color/Form	White, powder, needles from benzene Colorless crystalline solid White, crystalline powder Colorless needles
Density	1.4 (NTP, 1992) 1.400 g/cu cm at 25 °C 1.4 g/cm³
Flash Point	182 °C
Melting Point	264 to 268 °F (NTP, 1992) 130 °C 130.0 °C Mp 129-130 ° 128.8 °C 130°C 127-131 °C
Other CAS RN	98-92-0 11032-50-1
Physical Description	Nicotinamide is a white powder. (NTP, 1992) DryPowder; OtherSolid Solid WHITE CRYSTALLINE POWDER.
Pictograms	Irritant
Shelf Life	Stable under recommended storage conditions. ... Niacinamide is incompatible with alkalis and strong acids.
Solubility	greater than or equal to 100 mg/mL at 70° F (NTP, 1992) 500000 mg/L (at 25 °C) 4.09 M 500 mg/mL at 25 °C In water, 5X10+5 mg/L at 25 °C Very soluble in water; 1 g is soluble in 1 mL water 1 g dissolves in about 1 mL water, in 10 mL glycerol, in about 1.5 mL alcohol Soluble in butanol, chloroform Very soluble in 95% ethanol. Soluble in butanol, amyl alcohol, ethylene glycol, acetone and chloroform; slightly soluble in ether or benzene Very soluble in ethanol, glycerol; slightly soluble in chloroform Solubility in water, g/100ml at 20 °C: 100 (very good) 2.8 [ug/mL]
Synonyms	3 Pyridinecarboxamide;3-Pyridinecarboxamide;B 3, VitaminB3, VitaminEnduramide Jenapharm, Nicotinsäureamid;Niacinamide;Nicobion;Nicotinamide;Nicotinsäureamid Jenapharm;Papulex;Vitamin B 3;Vitamin B3;Vitamin PP
Vapor Density	Relative vapor density (air = 1): 4.2
Vapor Pressure	4.2X10-4 mm Hg at 25 °C (est) Vapor pressure, kPa at 35 °C: 3.1