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| Cat. Number | 080947460299773 |
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| Chemical Name | AFMK |
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| References |
Background ReadingHarthé, C., Claudy, D., Déchaud, H., et al. Radioimmunoassay of N- Tan, D., Manchester, L.C., Burkhardt, S., et al. N1- Hirata, F., Hayaishi, O., Tokuyama, T., et al. In vitro and in vivo formation of two new metabolites of melatonin. J Biol Chem 249(4) 1311-1313 (1974).
Description
Melatonin is a neurotransmitter widely distributed in eukaryotes and is closely linked to circadean rhythms in mammals including humans. AFMK is a melatonin metabolite first identified in rat brain.1 AFMK has antioxidant and free radical scavenging activities in several experimental models.2 AFMK may also be measured in plasma as an index of melatonin synthesis and metabolism.3
1 Hirata, F., Hayaishi, O., Tokuyama, T., et al. In vitro and in vivo formation of two new metabolites of melatonin. J Biol Chem 249(4) 1311-1313 (1974).
2
Tan, D., Manchester, L.C., Burkhardt, S., et al. N1-
3
Harthé, C., Claudy, D., Déchaud, H., et al. Radioimmunoassay of N- |
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