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| Cat. Number | 080650898523755 |
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| Chemical Name | Didox |
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| References |
Background ReadingTurchan, J., Pocernich, C.B., Gairola, C., et al. Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants. Neurology 60 307-314 (2003). Inayat, M.S., Chendil, D., Mohiuddin, M., et al. Didox (A novel ribonucleotide reductase inhibitor) Overcomes bcl-
Description
Polyhydroxylated aromatic compounds, both natural and synthetic, are important biological antioxidants. Didox is a simple, synthetic antioxidant that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.1 It also increases the radiosensitivity of cancer cells by inhibition of ribonucleotide reductase, resulting in a reduction of bcl-
1 Turchan, J., Pocernich, C.B., Gairola, C., et al. Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants. Neurology 60 307-314 (2003).
2
Inayat, M.S., Chendil, D., Mohiuddin, M., et al. Didox (A novel ribonucleotide reductase inhibitor) Overcomes bcl- |
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