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Cat. Number
080631410087526
Chemical Name
dimethoxy Curcumin
References
Formal Name 1,​7-​bis(3,​4-​dimethoxyphenyl)-​1,​6-​heptadiene-​3,​5-​dione
CAS Number 160096-59-3
Molecular Formula C23H24O6
Formula Weight 396.4
Formulation A crystalline solid
Purity ≥90%
λmax 418 nm
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES COC1=C(OC)​C=C(/C=C/C(CC(/C=C/C2=CC=C(OC)​C(OC)​=C2)​=O)​=O)​C=C1

Background Reading

Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).

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Description

Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. dimethoxy Curcumin is an analog of curcumin obtained by methylation of both free phenolic groups in the parent compound. A 30-fold increase in potency was observed in the growth suppression of HCT116 tumor cells following this modification. 1

1 Ohori, H., Yamakoshi, H., Tomizawa, M., et al. Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer. Mol Cancer Ther 5(10) 2563-2571 (2006).

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