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Cat. Number

080591287923950

Chemical Name

Ebselen Oxide

References

Synonyms	NSC 639772
Formal Name	1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number	104473-83-8
Molecular Formula	C₁₃H₉NO₂Se
Formula Weight	290.2
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O

Background Reading

Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys Acta 1303 111-118 (1996).

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Description

Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.¹

1 Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys Acta 1303 111-118 (1996).

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