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| Cat. Number | 080476504927617 |
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| Chemical Name | Genistein |
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| References |
Background ReadingNewbold, R.R., Banks, E.P., Bullock, B., et al. Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61 4325-4328 (2001). Lamartiniere, C.A., Cotroneo, M.S., Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. J Nutr 132 552S-558S (2002). Akiyama, T., Ishida, J., Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine-
Description
Genistein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, and other legumes. The estimated human normal dietary intake of genistein, primarily as glycosides, is 0 to 0.5 mg/kg. Genistein is present in much greater amounts in nutritional supplements. Genistein is carcinogenic in female neonatal mice, inducing endocrine-
1 Newbold, R.R., Banks, E.P., Bullock, B., et al. Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61 4325-4328 (2001).
2
Akiyama, T., Ishida, J., Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine- 3 Lamartiniere, C.A., Cotroneo, M.S., Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. J Nutr 132 552S-558S (2002). |
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