| References |
| Formulation |
100 µg of protein G-purified IgG in 100 µl PBS, pH 7.4, containing 50% glycerol and 0.09% sodium azide |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
|
| Specificity |
| Human HCN1 |
+ |
| Murine HCN1 |
+ |
| Rat HCN1 |
+ |
|
Background Reading
Zong, X., Eckert, C., Yuan, H., et al. A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by src kinase. J Biol Chem 280(40) 34224-34232 (2005).
. What are ion channels? (2004).
Hille, B. Ion Channels of Excitable Membranes. 3rd (2001).
| Size |
Global Purchasing |
| 100 µg |
|
Description
Antigen:
fusion protein amino acids 778-910 (cytoplasmic C-terminus) of rat HCN1
·
Clone designation:
S70-28
·
Host:
mouse
·
Isotype:
IgG1
·
Application(s):
WB, IP, IHC, and ICC
·
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulation of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain.1
1
Zong, X., Eckert, C., Yuan, H., et al. A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by src kinase. J Biol Chem 280(40) 34224-34232 (2005).
|