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/ Products Classification 点击展开+Cat. Number | 070346166585439 |
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Chemical Name | Hsp25/Hsp27 Monoclonal Antibody (Clone 8A7) |
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References |
Background ReadingWelsh, M.J., Wu, W., Parvinen, M., et al. Variation in expression of Hsp27 messenger ribonucleic acid during the cycle of the seminiferous epithelium and co- Welch, W.J. Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000- Jia, Y., Ransom, R.F., Shibanuma, M., et al. Identification and characterization of hic- Ciocca, D.R., Oesterreich, S., Chamness, G.C., et al. Biological and clinical implications of heat shock protein 27000 (Hsp27): A review. J Natl Cancer Inst 85 1558-1570 (1993). Sarto, C., Binz, P., and Mocarelli, P. Heat shock proteins in human cancer. Electrophoresis 21 1218-1226 (2000). Arrigo, A. In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation. J Cell Biochem 94 241-246 (2005). Kim, K.K., Kim, R., and Kim, S. Crystal structure of a small heat- Van Montfront, R., Slingsby, C., and Vierlingt, E. Structure and function of the small heat shock protein/crystallin family of molecular chaperones. Adv Protein Chem 59 105-156 (2001). Ehrnsperger, M., Gräber, S., Gaestel, M., et al. Binding of non-
Description
Antigen:
Hsp27 peptide
·
Clone designation:
8A7
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Host:
Mouse
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Application(s):
WB, immunofluorescence, ICC, IP
·
Heat shock protein 25 (Hsp25) is the murine homologue of the human Hsp27 protein, a member of the small Hsp family comprised of a diverse group of proteins from ~15 to >30 kDa.1 The basic structure of most Hsps is a homologous and highly conserved amino acid sequence, with an α-
1
Welch, W.J. Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-
2
Kim, K.K., Kim, R., and Kim, S. Crystal structure of a small heat- 3 Van Montfront, R., Slingsby, C., and Vierlingt, E. Structure and function of the small heat shock protein/crystallin family of molecular chaperones. Adv Protein Chem 59 105-156 (2001).
4
Ehrnsperger, M., Gräber, S., Gaestel, M., et al. Binding of non- 5 Ciocca, D.R., Oesterreich, S., Chamness, G.C., et al. Biological and clinical implications of heat shock protein 27000 (Hsp27): A review. J Natl Cancer Inst 85 1558-1570 (1993).
6
Welsh, M.J., Wu, W., Parvinen, M., et al. Variation in expression of Hsp27 messenger ribonucleic acid during the cycle of the seminiferous epithelium and co- 7 Sarto, C., Binz, P., and Mocarelli, P. Heat shock proteins in human cancer. Electrophoresis 21 1218-1226 (2000). 8 Arrigo, A. In search of the molecular mechanism by which small stress proteins counteract apoptosis during cellular differentiation. J Cell Biochem 94 241-246 (2005). |
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