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/ Products Classification 点击展开+Cat. Number | 070342341681475 |
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Chemical Name | Hsp40 Polyclonal Antibody |
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References |
Background ReadingMelville, M.W., Hansen, W.J., Freeman, B.C., et al. The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR. Proc Natl Acad Sci USA 94 97-102 (1997). Ohtsuka, K. Cloning of a cDNA for heat- Ohtsuka, K., Masuda, A., Nakai, A., et al. A novel 40- Hattori, H., Liu, L., Tohnai, I., et al. Intracellular localization and partial amino acid sequence of a stress- Bardwell, J.C.A., Tilly, K., Craig, E., et al. The nucleotide sequence of the Escherichia coli K12 dnaJ gene: A gene that encodes a heat shock protein. J Biol Chem 261(4) 1782-1785 (1986). Ohki, M., Tamura, F., Nishimura, S., et al. Nucleotide sequence of the escherichia coli dnaJ gene and purification of the gene product. J Biol Chem 261(4) 1778-1781 (1986). Show all 6 Hide all but first 3
Description
Antigen:
human recombinant Hsp40
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Host:
rabbit
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Application(s):
WB
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DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ11, is a basic mammalian 40 kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-
1
Ohtsuka, K. Cloning of a cDNA for heat-
2
Hattori, H., Liu, L., Tohnai, I., et al. Intracellular localization and partial amino acid sequence of a stress-
3
Ohtsuka, K., Masuda, A., Nakai, A., et al. A novel 40- 4 Bardwell, J.C.A., Tilly, K., Craig, E., et al. The nucleotide sequence of the Escherichia coli K12 dnaJ gene: A gene that encodes a heat shock protein. J Biol Chem 261(4) 1782-1785 (1986). 5 Ohki, M., Tamura, F., Nishimura, S., et al. Nucleotide sequence of the escherichia coli dnaJ gene and purification of the gene product. J Biol Chem 261(4) 1778-1781 (1986). |
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