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Cat. Number
070265184420710
Chemical Name
I2PP2A/SET Polyclonal Antibody
References
Synonyms
  • Phosphatase 2A Inhibitor
  • Template-Activating Factor I
  • Inhibitor of granzyme A-activated DNase
  • PHAPII
Formulation 100 µl of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide and 0.1 mg/ml BSA
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human I2PP2A/SET +
Size Global Purchasing
1 ea  

Description

Antigen: synthetic peptides from human I2PP2A/SET amino acids 79-94 and 148-164 · Host: Rabbit · Application(s): WB · I2PP2A/SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly, and histone binding. The SET gene produces two isoforms from transcript variants. Isoform 1 and 2 interact directly with each other and with ANP32A within the tripartite inhibitor of acetyltransferases (INHAT) complex, inhibiting EP300/CREBBP and PCAF-mediated acetylation of histones. The two isoforms differ in their amino termini but are identical through the regions used as antigens for preparing this antibody.
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