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Cat. Number

070064633131973

Chemical Name

JMJD2D Polyclonal Antibody

References

Synonyms

Jumonji Domain Containing 2D
Lysine-Specific Demethylase 4D
KDM4D

Formulation

antigen-affinity purified rabbit IgG in 500 μl TBS, pH 7.4, containing 50 % glycerol, 0.5 mg/ml BSA, and 0.02 % sodium azide

Stability

1 year

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Specificity

Human JMJD2D	+
Murine JMJD2D	+

Background Reading

Metzger, E., and Schüle, R. The expanding world of histone lysine demethylases. Nat Struct Mol Biol 14(4) 252-254 (2007).

Cloos, P.A.C., Christensen, J., Agger, K., et al. The putative oncogene GASC1 demethylates tri- and imethylated lysine 9 on histone H3. Nature 442 307-311 (2006).

Lan, F., Nottke, A.C., and Shi, Y. Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Chem Biol 20 316-325 (2008).

Size	Global Purchasing
500 µl

Description

Antigen: human recombinant JMJD2D amino acids 1-354 · Host: rabbit · Application(s): FC, ICC, IP, and WB · Jumonji Domain Containing 2D (JMJD2D) is a lysine specific demethylase with emerging roles in histone modification or epigenetic remodeling.¹ This JMJD2D polyclonal antibody was raised against a N-terminal recombinant fragment of JMJD2D. JMJD2D is detected at 60 kDa by western blotting using a DLD1 cell lysate as a positive control.

1 Metzger, E., and Schüle, R. The expanding world of histone lysine demethylases. Nat Struct Mol Biol 14(4) 252-254 (2007).

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