| Synonyms |
- Amine Oxidase (flavin containing) Domain 2
|
| Formulation |
100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
|
| Specificity |
| Canine LSD1 |
+ |
| Human LSD1 |
+ |
| Murine LSD1 |
+ |
| Rat LDS1 |
+ |
| Rhesus monkey LSD1 |
+ |
| Zebrafish LSD1 |
+ |
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|
| Size |
Global Purchasing |
| 1 ea |
|
Description
Antigen:
synthetic peptide corresponding to a portion of human LSD1 amino acids 100-150
·
Host:
rabbit
·
Application(s):
WB
·
LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.
