| Synonyms |
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| Formulation |
100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
|
| Specificity |
|
Background Reading
Creasy, C.L., and Chernoff, J. Cloning and characterization of a human protein kinase with homology to Ste20. J Biol Chem 270(37) 21695-21700 (1995).
| Size |
Global Purchasing |
| 1 ea |
|
Description
Antigen:
synthetic peptide from human MST-1 amino acids 372-390
·
Host:
Rabbit
·
Application(s):
WB
·
Mammalian STE-20-like kinase 1 (MST-1) is a serine/threonine kinase that, upon cleavage, has been implicated in the promotion of chromatin condensation. The C-terminus of MST-1 contains two functional nuclear export signals (NESs), which are released upon caspase-mediated cleavage. The N-terminus portion of the protein then translocates to the nucleus and promotes chromatin condensation at sufficiently high levels. Full-length MST-1 is localized to the cytoplasm.
