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Cat. Number
069765966058739
Chemical Name
MutL Protein Homolog 1 Monoclonal Antibody (Clone 164C819)
References
Synonyms
  • HNPCC
  • MLH1
Stability 6 months
Storage 4°C
Specificity
Human MLH1 +

Background Reading

Bronner, C.E., Baker, S.M., Morrison, P.T., et al. Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer. Nature 368 258-261 (1994).

Brown, R., Hirst, G.L., Gallagher, W.M., et al. hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene 15 45-52 (1997).

Grady, W.M., Rajput, A., Lutterbaugh, J.D., et al. Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer. Cancer Res 61 900-902 (2001).

Size Global Purchasing
1 ea  

Description

Antigen: synthetic peptide from human MLH1 amino acids 387-403 · Clone designation: 164C819 · Host: mouse · Isotype: IgG1κ · Application(s): WB · Human MutL Homologue (hMLH1) is homologous to the bacterial DNA mismatch repair mutL gene. Mutations in the hMLH1 gene are associated with hereditary non-polyposis colon cancer and various other cancers.
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