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仪器耗材

Cat. Number
069739219804666
Chemical Name
Nampt Monoclonal Antibody (Clone OMNI 379)
References
Synonyms
  • Nicotinamide Phosphoribosyltransferase
  • Pre-B Cell Colony Enhancing Factor 1
  • Visfatin
  • PBEF1
Formulation A 1 mg/ml solution in PBS, pH 7.4
Stability 6 months
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human Nampt +
Mouse Nampt +
Rat Nampt +
Size Global Purchasing
50 µg  
100 µg  

Description

Antigen: recombinant human Nampt · Clone designation: OMNI 379 · Host: mouse · Isotype: IgG2aκ · Application(s): ELISA, FC, ICC, IHC, IP, and WB · Nampt is a 52 kDa adipokine secreted by adipose tissue that is involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates the insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
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