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Cat. Number
069428551654461
Chemical Name
Prion Protein Monoclonal Antibody (308)
References
Formulation 200 µg lyophilized IgG containing 200 µg BSA
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Hamster Prion Protein +
Murine Prion Protein +
Ovine Prion Protein +
Human Prion Protein +
Bovine Prion Protein -
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Background Reading

Brown, D.R., Qin, K., Herms, J.W., et al. The cellular prion protein binds copper in vivo. Nature 390 684-687 (1997).

Bolton, D.C., McKinley, M.P., and Prusiner, S.B. Identification of a protein that purifies with the scrapie prion. Science 218 1309-1311 (1982).

Marcotte, E.M., and Eisenberg, D. Chicken prion tandem repeats form a stable, protease-resistant domain. Biochemistry 38 667-676 (1999).

Liao, Y.J., Lebo, R.V., Clawson, G.A., et al. Human prion protein cDNA: Molecular cloning, chromosomal mapping, and biological implications. Science 233 364-367 (1986).

Pauly, P.C., and Harris, D.A. Copper stimulates endocytosis of the prion protein. J Biol Chem 273 33107-33110 (1998).

Prusiner, S.B. Prions. Proc Natl Acad Sci USA 95 13363-13383 (1998).

Prusiner, S.B. Prion diseases and the BSE crisis. Science 278 245-251 (1997).

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Size Global Purchasing
1 ea  

Description

Antigen: human prion amino acids 106-126 (GAAAAGAVVGGLGGYMLGSAM) · Host: mouse · Isotype: IgG1 · Application(s): IHC and WB ·
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