| Synonyms |
- Protein Arginine Methyltransferase 7
- Skb1HS
- JBP1
|
| Formulation |
200 µl of protein G-purified IgG in PBS containing 0.02% sodium azide |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
|
| Specificity |
|
| Size |
Global Purchasing |
| 1 ea |
|
Description
Antigen:
synthetic peptide from human PRMT5
·
Host:
rabbit
·
Application(s):
WB
·
Protein arginine methylation is an important post-translational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT5, also known as Janus kinase-binding protein 1 (JBP1) and human homolog of Skb1 of fission yeast (Skb1HS) can catalyze the formation of ω-NG-monomethylarginine and symmetric w-NG,NG’-dimethylarginine in a varity of proteins. Recombinant PRMT5 can mono and dimethylate histone 2A and myelin basic protein. PRMT5 appears to have lower specific enzyme activity than PRMT1.
