您的位置:首页>>Cayman>>Antibodies>>PRMT7 Polyclonal Antibody
Cat. Number
069337405516158
Chemical Name
PRMT7 Polyclonal Antibody
References
Synonyms
  • Protein Arginine Methyltransferase 7
Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human PRMT7 +
Murine PRMT7 +
Size Global Purchasing
1 ea  

Description

Antigen: synthetic peptide from human PRMT7 amino acid sequence 346-360 · Host: rabbit · Application(s): WB · Protein arginine methylation (PRMT) is an important post-translational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. The PRMT proteins are recruited by C-terminal acitvation domain-2 of the steroid receptor coactivator (SRC) GRIP-1, whereas p300 interacts with activation domain-1 in the C-terminus. Researchers have identified a mammalian arginine N-methyltransferase, PRMT7, that can catalyze the formation of w-NG-monomethylarginine in peptides. In contrast to other members of the PRMT family, PRMT7 was not able to methylate GST-fibrillarin or myelin basic protein or histone H2A, in vitro. It is also structurally different from other PRMTs in containing two putative AdoMet-binding motifs. Both of these domains are required for enzymatic activity.
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