| Synonyms |
- Sphingosine-1-phosphate Receptor 4
- S1PR4
- EDG-6
|
| Formulation |
00 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
|
| Specificity |
| Human S1P4 |
+ |
| Murine S1P4 |
+ |
|
| Size |
Global Purchasing |
| 1 ea |
|
Description
Antigen:
synthetic peptide from human S1P4 within the region of amino acids 1-50
·
Host:
rabbit
·
Application(s):
WB, IF, and ICC
·
EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family and is a receptor for sphingosine 1-phosphate (S1P). Binding of S1P to EDG-6 activates Erk, leading to the activation of the transcription factor Elk1 and thus the mitogen-activated protein kinase (MAPK) signal transduction pathway. The protein is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Human EDG-6 gene is intronless and is mapped to chromosome 19p13.3 at the D19S120 marker.
