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Cat. Number
068705997395252
Chemical Name
TRF4-1 Polyclonal Antibody
References
Synonyms
  • DNA Polymerase σ
  • DNA Polymerase κ
  • PAP-Associated Domain-Containing Protein 7
Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human TRF4-1 +

Background Reading

Castaño, I.B., Brzoska, P.M., Sadoff, B.U., et al. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Genes Dev 10 2564-2576 (1996).

Castaño, I.B., Heath-Pagliuso, S., Sadoff, B.U., et al. A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation. Nucleic Acids Res 24(12) 2404-2410 (1996).

Size Global Purchasing
1 ea  

Description

Antigen: synthetic peptide corresponding to human TRF4-1 amino acids 447-462 · Host: Rabbit · Application(s): WB · TRF4-1 is a nuclear protein whose expression is cell cycle-regulated at a post-transcriptional level.1,2 Two genes TRF4-1 and TRF4-2, belonging to this family have been identified. TRF4 is also required to maintain a different aspect of higher order chromosome structure, sister chromatid cohesion.

1 Castaño, I.B., Brzoska, P.M., Sadoff, B.U., et al. Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae. Genes Dev 10 2564-2576 (1996).

2 Castaño, I.B., Heath-Pagliuso, S., Sadoff, B.U., et al. A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation. Nucleic Acids Res 24(12) 2404-2410 (1996).

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