(±)-CP 47,497 is a synthetic cannabinoid (CB) that avidly binds the CB1 receptor (Ki = 2.2 nM) and is equivalent in analgesic potency to Δ9-THC.1,2 (±)-epi CP 47,497 is an epimer of (±)-CP 47,497. This compound is intended to be used as an analytical standard.
1
Huffman, J.W., Thompson, A.L.S., Wiley, J.L., et al. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg Med Chem 16 322-335 (2008).
2
Melvin, L.S., Milne, G.M., Johnson, M.R., et al. Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: Studies of bicyclic cannabinoid analogs. Mol Pharmacol 44 1008-1015 (1993).