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Cat. Number
652626508206738
Chemical Name
5(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester
References
Synonyms
  • Mead Acid methyl ester
Formal Name 5Z,​8Z,​11Z-​eicosatrienoic acid,​ methyl ester
Molecular Formula C21H36O2
Formula Weight 320.5
Formulation A solution in hexane
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES CCCCCCCCC=C/C/C=CC/C=CCCCC(OC)​=O
Size Global Purchasing
1 mg  
5 mg  
10 mg  

Description

Mead acid is a 20-carbon ω-9 polyunsaturated fatty acid. Its level is elevated in plasma during essential fatty acid deficiency in humans.1,2 5(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester (Mead acid methyl ester) is typically used as a standard for the analysis of fatty acids, when the fatty acids have been transesterified to methyl esters before analysis.3,4

1 Siguel, E.N., Chee, K.M., Gong, J., et al. Criteria for essential fatty acid deficiency in plasma as assessed by capillary column gas-liquid chromatography. Clin Chem 33(10) 1869-1873 (1987).

2 Farrell, P.M., Gutcher, G.R., Palta, M., et al. Essential fatty acid deficiency in premature infants. Am J Clin Nutr 48 220-229 (1988).

3 Lepage, G., and Roy, C.C. Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27 114-120 (1986).

4 Masood, A., Stark, K.D., and Salem, N. A simplified and efficient method for the analysis of fatty acid methyl esters suitable for large clinical studies. J Lipid Res 46 2299-2305 (2005).

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