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| Cat. Number | 288261225883856 |
| Chemical Name | AZD 5438 |
| CAS Number | [602306-29-6] |
| Mol. Formula | C18H21N5O2S |
| Mol. Weight | 371.46 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-[2-Methyl-1-(1-methylethyl)-1H-im idazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimi dinamine |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Potent inhibitor of cyclin-dependent kinase (cdk) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively). Exhibits antiproliferative activity in human tumor cell lines. Blocks cell cycling at G2-M, S and G1 phases; reduces the proportion of actively cycling cells in vivo. Purity: >99 % |
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