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| Cat. Number | 288231507944822 |
| Chemical Name | AZ 11645373 |
| CAS Number | [227088-94-0] |
| Mol. Formula | C24H21N3O5S |
| Mol. Weight | 463.51 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-[1-[[(3'-Nitro[1,1'-biphenyl]-4-yl) oxy]methyl]-3-(4-pyridinyl)propyl]-2,4-thiazolidin edione |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent and selective human P2X7 antagonist (KB values are 5 - 7 and > 10,000 nM at hP2X7 and rP2X7 respectively) that is completely without effect at all other P2X subtypes. Inhibits BzATP-mediated calcium influx and inhibits ATP-mediated IL-1β release in vitro (KB values are 15 and 92 nM respectively). Purity: >98 % |
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