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Cat. Number
288224590522027
Chemical Name
AZ 10606120 dihydrochloride
Mol. Formula
C25H34N4O2.2HCl
Mol. Weight
495.48
Qty 1
10mg
Qty 2
50mg
Synonym
N-[2-[[2-[(2-Hydroxyethyl)amino]eth yl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec- 1-ylacetamide dihydrochloride
Solubility
Soluble to 25 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Potent P2X7 receptor antagonist (KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively). Binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding site and acts as a negative allosteric modulator.
Purity: >98 %
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