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/ Products Classification 点击展开+Cat. Number | 288224590522027 |
Chemical Name | AZ 10606120 dihydrochloride |
Mol. Formula | C25H34N4O2.2HCl |
Mol. Weight | 495.48 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[2-[[2-[(2-Hydroxyethyl)amino]eth yl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec- 1-ylacetamide dihydrochloride |
Solubility | Soluble to 25 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Potent P2X7 receptor antagonist (KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively). Binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding site and acts as a negative allosteric modulator. Purity: >98 % |
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