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Cat. Number
288216988383983
Chemical Name
AZ 10417808
CAS Number
[331645-84-2]
Mol. Formula
C18H13C12N5O4
Mol. Weight
434.23
Qty 1
10mg
Qty 2
50mg
Synonym
2-[(3,4-Dichlorophenyl)amino]-1,4-d ihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecar boxamide
Solubility
Soluble to 25 mM in DMSO
Storage condition
Store at RT
References
Selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC50 = 14.9 μM).
Purity: >98 %
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