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| Cat. Number | 288200483748120 |
| Chemical Name | AY 9944 dihydrochloride |
| CAS Number | [366-93-8] |
| Mol. Formula | C22H28Cl2N2.2HCl |
| Mol. Weight | 464.3 |
| Qty 1 |
10mg |
| Synonym | trans-N,N-bis[2-Chlorophenylmethyl] -1,4-cyclohexanedimethanamine dihydrochloride |
| Solubility | Soluble to 50 mM in water |
| Storage condition | Desiccate at RT |
| References | Inhibitor of hedgehog (Hh) signaling, possibly via several mechanisms. Inhibits Δ7-dehydrocholesterol reductase (IC50 = 13 nM), thus reduces cholesterol biosynthesis, and also inhibits cholesterol esterification. May also directly block the cellular response to Hh proteins. Teratogenic in vivo. Purity: >99 % |
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