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/ Products Classification 点击展开+Cat. Number | 288131779008791 |
Chemical Name | ATC 0175 hydrochloride |
CAS Number | [510733-97-8] |
Mol. Formula | C23H25F2N5O.HCl |
Mol. Weight | 461.94 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[cis-4-[[4-(Dimethylamino)-2-quin azolinyl]amino]cyclohexyl]-3,4-difluorobenzamide hydrochloride |
Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
Storage condition | Store at +4°C |
References | Potent, selective and orally active melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 values are 13.5 and > 10000 nM for MCH1 and MCH2 receptors respectively). Exhibits anxiolytic and antidepressant activity in rodents. Also displays affinity for 5-HT2B and 5-HT1A receptors (IC50 values are 9.66 and 16.9 nM respectively). Purity: >98 % |
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