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Cat. Number
288131779008791
Chemical Name
ATC 0175 hydrochloride
CAS Number
[510733-97-8]
Mol. Formula
C23H25F2N5O.HCl
Mol. Weight
461.94
Qty 1
10mg
Qty 2
50mg
Synonym
N-[cis-4-[[4-(Dimethylamino)-2-quin azolinyl]amino]cyclohexyl]-3,4-difluorobenzamide hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at +4°C
References
Potent, selective and orally active melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 values are 13.5 and > 10000 nM for MCH1 and MCH2 receptors respectively). Exhibits anxiolytic and antidepressant activity in rodents. Also displays affinity for 5-HT2B and 5-HT1A receptors (IC50 values are 9.66 and 16.9 nM respectively).
Purity: >98 %
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