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| Cat. Number | 288039992888098 |
| Chemical Name | AS 605240 |
| CAS Number | [648450-29-7] |
| Mol. Formula | C12H7N3O2S |
| Mol. Weight | 257.27 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5-(6-Quinoxalinylmethylene)-2,4-thi azolidine-2,4-dione |
| Solubility | Soluble to 1 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent and selective inhibitor of PI 3-kinase γ (PI3Kγ) (IC50 = 8 nM). Displays 30-fold selectivity over PI3Kδ and PI3Kβ and 7.5-fold selectivity over PI3Kα. Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive. Purity: >98 % |
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