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/ Products Classification 点击展开+Cat. Number | 287947128446885 |
Chemical Name | ARL 17477 dihydrochloride |
CAS Number | [180983-17-9] |
Mol. Formula | C20H20ClN3S.2HCl |
Mol. Weight | 442.83 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-[4-[2-[[(3-Chlorophenyl)methyl]am ino]ethyl]phenyl]-2-thiophenecarboxamide dihydrochloride |
Solubility | Soluble to 50 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Selective neuronal nitrogen oxide synthase (nNOS) inhibitor (IC50 values are 1 and 17 μM for nNOS and endothelial NOS respectively). Reduces ischemic cell damage after middle cerebral artery (MCA) occlusion in rats. Displays a synergistic neuroprotective effect when combined with either an NMDA or AMPA receptor antagonist. Purity: >99 % |