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Cat. Number
287947128446885
Chemical Name
ARL 17477 dihydrochloride
CAS Number
[180983-17-9]
Mol. Formula
C20H20ClN3S.2HCl
Mol. Weight
442.83
Qty 1
10mg
Qty 2
50mg
Synonym
N-[4-[2-[[(3-Chlorophenyl)methyl]am ino]ethyl]phenyl]-2-thiophenecarboxamide dihydrochloride
Solubility
Soluble to 50 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at RT
References
Selective neuronal nitrogen oxide synthase (nNOS) inhibitor (IC50 values are 1 and 17 μM for nNOS and endothelial NOS respectively). Reduces ischemic cell damage after middle cerebral artery (MCA) occlusion in rats. Displays a synergistic neuroprotective effect when combined with either an NMDA or AMPA receptor antagonist.
Purity: >99 %
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