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| Cat. Number | 287791159774291 |
| Chemical Name | Apoptosis Activator 2 |
| CAS Number | [79183-19-0] |
| Mol. Formula | C15H9Cl2NO2 |
| Mol. Weight | 306.14 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-[(3,4-Dichlorophenyl)methyl]-1H-i ndole-2,3-dione |
| Solubility | Soluble to 5 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Store at RT |
| References | Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM). Purity: >99 % |
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