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Cat. Number
287766760138577
Chemical Name
API-1
CAS Number
[36707-00-3]
Mol. Formula
C13H15N5O6
Mol. Weight
337.29
Qty 1
10mg
Synonym
4-Amino-5,8-dihydro-5-oxo-8-β-D-ribo furanosyl-pyrido[2,3-d]pyrimidine-6-carboxamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Akt/protein kinase B (PKB) inhibitor. Binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation. Inhibits EGF-induced kinase activity of Akt1, AKT2 and AKT3. Activity results in cell growth arrest and apoptosis in human cancer cells with constitutively active Akt. Displays antitumor activity in vitro and in vivo.
Purity: >96 %
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