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Cat. Number
287546668280502
Chemical Name
AP 18
CAS Number
[55224-94-7]
Mol. Formula
C11H12CINO
Mol. Weight
209.67
Qty 1
10mg
Qty 2
50mg
Synonym
4-(4-Chlorophenyl)-3-methyl-3-buten -2-one oxime
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Reversible TRPA1 channel blocker (IC50 values are 3.1 and 4.5 μM at human and mouse TRPA1 respectively). Blocks cinnameldehyde-induced but not capsaicin-induced nociception and reverses mechanical hyperalgesia in vivo. Also blocks TRPA1 pore dilation (IC50 = 10.3 μM for the inhibition of Yo-Pro uptake).
Purity: >98 %
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