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Cat. Number
287515639769930
Chemical Name
Antagonist G
CAS Number
[115150-59-9]
Mol. Formula
C49H66N12O6S
Mol. Weight
951.2
Qty 1
1mg
Storage condition
Desiccate at -20°C
References
Substance P analog that is a broad spectrum neuropeptide antagonist and antiproliferative agent. Blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. Inhibits neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro; activates JNK and stimulates apoptosis. Inhibits growth of SCLC xenografts in mice in vivo.
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