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/ Products Classification 点击展开+Cat. Number | 287108105290921 |
Chemical Name | AM 80 |
CAS Number | [94497-51-5] |
Mol. Formula | C22H25NO3 |
Mol. Weight | 351.44 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tet ramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid |
Solubility | Soluble to 100 mM in 1.1eq. NaOH and to 50 mM in DMSO |
Storage condition | Store at RT |
References | Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo. Purity: >99 % |
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