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Cat. Number
287098231096802
Chemical Name
AM 580
CAS Number
[102121-60-8]
Mol. Formula
C22H25NO3
Mol. Weight
351.44
Qty 1
10mg
Qty 2
50mg
Synonym
4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetr amethyl-2-naphthalenyl)carboxamido]benzoic acid
Solubility
Soluble to 50 mM in DMSO
Storage condition
Store at RT
References
An analog of retinoic acid that acts as a selective RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFNγ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro.
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